利用UPLC—Q—TOF—MSE快速分析四物汤中的化学成分(5)
Siwu decoction by UPLC-Q-TOF-MSE
WANG Zhen-fang1，2， ZHAO Yang1 ， PANG Xu1 ， YU He-shui1，2 ， KANG Li-ping1 ， GAO Yue1 ， MA Bai-ping1*
(1、Institute of Radiation Medicine， Academy of Military Medical Sciences， Beijing 100850， China；
2、 Tianjin University of Traditional Chinese Medicine， Tianjin 300193， China)
[Abstract] This research analyzed the chemical constituents of Siwu decoction by UPLC-Q-TOF-MSE、 Base on the data of mass and related-literatures， 43 peaks were profiled and 25 compounds， which contain 8 monoterpene glycosides from Paeonia lactiflora and 13 phthalides from Rhizoma chuanxiong and Radix angelica sinensis mainly， were identified in both positive and negative mode respectively、 Meanwhile， chemical constituents of water extract and 60% ethanol extract of Siwu decoction were compared by the principal constituent analysis with MarkerLynx software， which provides the basis for the active ingredients of Siwu decoction、[Key words] Siwu decoction； UPLC-Q-TOF-MSE ； chemical constituents； MarkerLynx； method of extraction
doi：10.4268/cjcmm20132120
[责任编辑 孔晶晶], 百拇医药(王镇方 赵阳 庞旭 余河水 康利平 高月 马百平)
WANG Zhen-fang1，2， ZHAO Yang1 ， PANG Xu1 ， YU He-shui1，2 ， KANG Li-ping1 ， GAO Yue1 ， MA Bai-ping1*
(1、Institute of Radiation Medicine， Academy of Military Medical Sciences， Beijing 100850， China；
2、 Tianjin University of Traditional Chinese Medicine， Tianjin 300193， China)
[Abstract] This research analyzed the chemical constituents of Siwu decoction by UPLC-Q-TOF-MSE、 Base on the data of mass and related-literatures， 43 peaks were profiled and 25 compounds， which contain 8 monoterpene glycosides from Paeonia lactiflora and 13 phthalides from Rhizoma chuanxiong and Radix angelica sinensis mainly， were identified in both positive and negative mode respectively、 Meanwhile， chemical constituents of water extract and 60% ethanol extract of Siwu decoction were compared by the principal constituent analysis with MarkerLynx software， which provides the basis for the active ingredients of Siwu decoction、[Key words] Siwu decoction； UPLC-Q-TOF-MSE ； chemical constituents； MarkerLynx； method of extraction
doi：10.4268/cjcmm20132120
[责任编辑 孔晶晶], 百拇医药(王镇方 赵阳 庞旭 余河水 康利平 高月 马百平)