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编号:12778136
血管回声跟踪技术评价颈动脉斑块危险度分层(1)
http://www.100md.com 2015年12月15日 中国医药科学 2015年第24期
     [摘要] 目的 应用回声跟踪技术(ET)研究中老年患者颈动脉斑块弹性及应力改变与脑梗死的关系。 方法 研究对象分为脑梗死组和非脑梗死组。应用ET技术检测2008年3月~2015年6月,在鄂尔多斯市中心医院诊断为脑梗死的43例住院患者颈动脉斑块74个,及同期体检的44例非脑梗死者的颈动脉斑块74个。在脑梗死组与非脑梗死组的稳定斑块之间和非稳定斑块之间分别比较弹性指标,发现斑块弹性和应力改变与脑梗死的关系。 结果 稳定斑块组间比较,脑梗死组患者的Eρ、β均较非脑梗死组增高,差异有统计学意义(P<0.05);AC、δ差异无统计学意义(P>0.05)。不稳定斑块组间比较,脑梗死组患者的Eρ、β均较非脑梗死组增高,差异有统计学意义(P<0.05);AC、δ差异无统计学意义(P>0.05)。 结论 脑梗死组的稳定和不稳定斑块的Eρ、β均较非脑梗死组的高,两项指标结合斑块回声特征,可作为评价颈动脉斑块的危险度指标,为斑块危险度分层。

    [关键词] 超声诊断;颈动脉斑块;脑梗死;回声跟踪技术;斑块危险度
, http://www.100md.com
    [中图分类号] R541.4 [文献标识码] A [文章编号] 2095-0616(2015)24-07-05

    [Abstract] Objective To study correlations of carotid plaques elasticity and change of stress and cerebral infarction in elderly patients by using echo-tracking (ET) technique. Methods 74 carotid plaques of 43 hospitalized patients who were diagnosed as cerebral infraction group in Ordos Central Hospital from March 2008 to June 2015 were detected by ET technique.At the same time,74 carotid plaques of 44 non- cerebral infraction patients who were received healthy examinations were also detected by ET technique.Elasticity indexes were compared between stable plaques and unstable plaques in the cerebral infraction group and the non-cerebral infraction group to discover correlations of carotid plaques elasticity and change of stress and cerebral infarction. Results In comparison of stable plaques in two groups,Eρ and β of the cerebral infarction group were both increased compared with non-cerebral infarction group.There was significant difference(P<0.05).AC and δ had no statistical significance(P>0.05).In comparison of unstable plaques in two groups,Eρ and β of the cerebral infarction group were both higher than those of the non-cerebral infarction group.The difference had statistical significance(P<0.05).AC and δ had no statistical significance(P>0.05). Conclusion Eρ and β of stable plaques and unstable plaques in the cerebral infraction group were both higher than those of the non- cerebral infraction group.These two indexes combined with the character of plaque echo can be used as the index to evaluate and stratify the risk of plaques.
, 百拇医药
    [Key words] Ultrasound diagnosis;Carotid plaque;Cerebral infarction;Echo tracking technique;Risk of plaque

    脑卒中以其高死亡率和高致残率,目前已经成为威胁国人健康的首位疾病,2011年卫生部发布的《脑卒中宣言》称之为国民的“头号杀手”。用超声观察斑块的形态,用回声跟踪技术(echo tracking,ET)检测动脉粥样硬化(atherosclerosis,AS)患者颈动脉弹性和应力指标,两者相结合对颈动脉斑块的危险度进行分层。为临床预测和及早干预,避免发生脑血管意外提供可靠的评价指标。

    1 资料与方法

    1.1 一般资料

    脑梗死组为2008年3月~2015年6月在我院神经内科住院的脑梗死患者43例,并经超声检查发现颈动脉斑块。年龄50~80岁,平均(65.5±6.6)岁,其中男33例,女10例。共测量斑块74个。非脑梗死组为同期在我院体检发现颈动脉斑块的患者44例。年龄50~78岁,平均(64.3±6.1)岁,其中男31例,女13例,共测量斑块74个。所有患者均经头部CT或MRI检查,脑梗死的诊断符合第四届全国脑血管病会议所修订的标准[1]。, http://www.100md.com(李汇文 刘志跃 杨敬英 王金锐 张婷 徐霞)
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