[摘要] 目的 观察红蓝光联合维胺脂治疗中重度痤疮115例临床应用效果及安全性，探讨其临床适用性。 方法 选择自2013年1月～2014年6月于我院治疗的中重度痤疮患者330例，随机分为试验组和对照组各115例。观察并记录两组患者的临床疗效；对两组患者治疗前后进行GAGS评分；统计两组患者治疗前后皮疹改善情况；记录两组患者并发症发生情况。 结果 试验组和对照组的有效率分别为85.2%和61.7%，差异具有统计学意义(P<0.05)；两组治疗后GAGS评分改善显著，差异有统计学意义(P<0.05)；试验组皮疹改善情况优于对照组，差异有统计学意义(P<0.05)；两组患者并发症发生情况比较，差异无统计学意义(P>0.05)。 结论 红蓝光联合维胺脂治疗中重度痤疮临床效果显著，安全性高，适合临床长期推广应用。

    [关键词] 红蓝光；维胺脂；中重度痤疮；安全性

    [中图分类号] R758.733 [文献标识码] B [文章编号] 2095-0616(2016)01-68-04

    [Abstract] Objective To observe clinical applicative effect and safety of red and blue light combined with viaminate in treatment of severe acne in 115 cases and to explore its clinical applicability. Methods 330 patients with moderate to severe acne who were treated in our hospital from January 2013 to June 2014 were selected and they were randomly divided into the experimental group and control group ......