【摘 要】 目的：探讨联用TCT和HPV原位杂交检测对宫颈癌及癌前病变检出率的影响。方法：选取在本院接受宫颈癌及癌前病变筛查的1230例女性为研究对象，均采用TCT和HPV原位杂交联合检测，同时对其进行病理组织活检。结果：根据病理组织活检结果，本组1230例患者中为阳性的患者有59例，阳性率为4.80%;TCT和HPV原位杂交联合检测中阳性的患者有56例，阳性率为4.55%，病理组织活检的阳性率与联合检测的阳性率比较差异无统计学意义(P>0.05)。TCT和HPV原位杂交联合检测的诊断准确率为94.92%(56/59)，漏诊率为5.08%(3/59)。结论：TCT和HPV原位杂交联合检测在宫颈癌及癌前病变的筛查中具有较高的应用价值，可以提高宫颈癌及癌前病变的检出率和诊断准确率。

    【关键词】 TCT;HPV原位杂交;宫颈癌;癌前病变

    文章编号：WHR2020024015

    [Abstract] Objective：To investigate the effect of TCT and HPV in situ hybridization on the detection rate of cervical cancer and precancerous lesions. Methods： 1230 women who were screened for cervical cancer and precancerous lesions in our hospital were selected as the study objects. TCT and HPV in situ hybridization were performed in all the selected subjects ......