温肾化浊、逐瘀通络为主治疗糖尿病肾病的临床观察(1)
摘要目的：觀察温肾化浊、逐瘀通络为主治疗糖尿病肾病的临床疗效。方法：选取2014年2月至2016年2月在广东省东莞市虎门中医院内科门诊确诊和住院后出院转门诊的糖尿病肾病患者60例，采用随机单盲数字分组法随机分为观察组和对照组，每组30例。温肾化浊为对照组、逐瘀通络组为观察组。治疗3个月后，观察2组患者治疗前后生化指标、症状积分，比较2组的治疗效果。结果：治疗后2组FBG、HbA1C和TG等指标均有改善，2组患者治疗前后HbAlc、TG、24 h尿蛋白定、UAER比较差异有统计学意义(P<005)；2组治疗前后BuN、Cr、CysC、CH、hsCRP比较差异无统计学意义(P>005)。治疗后2组组间比较，观察组24 h尿蛋白定明显减少，差异有统计学意义(P<005)。观察组显效率100%，对照组90%，2组比较差异有统计学意义(P<005)。2组患者均未出现不良反应。结论：温肾化浊、逐瘀通络为主治疗糖尿病肾病结合西药常规治疗糖尿病肾病疗效优于单纯西药常规治疗。
关键词糖尿病肾病；中西医结合疗法；温肾化浊；逐瘀通络
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Clinical Observation of Treating Diabetic Nephropathy with Warming Kidney and Dissolving Turbidity and Removing Stasis and Dredging Collaterals Method
Song Songwen1，Zeng Qi1，Wu Xinmin1，Song Yinzhi2
(1 Internal Medicine Department of Humen Chinese Medicine Hospital，Dongguan 523939，China； 2 Cardiovascular Department of Baoan Chinese Hospital，Shenzhen 523900，China)
AbstractObjective：To observe the clinical efficacy of warming kidney and dissolving turbidity and removing stasis and dredging collaterals method in the treatment of diabetic nephropathy.Methods：From February 2014 to 2016，60 patients with diabetic nephropathy in our outpatient hospital were randomly collected and divided into two groups：the treatment group(using Chinese method) and the control group(using western medicine).After 3 months of treatment，two groups were observed before and after treatment for biochemical index and symptom scores，and the therapeutic effect of two groups were compared.Results：After treatment，FBG，HbAlc，TG and other indicators have improved，before and after treatment，HbAlc，TG，24 h urine protein set，UAER of the two groups were significantly different (P<005).Before and after treatment，BuN，Cr，CysC，CH，hsCRP showed no significant difference between the two groups (P>005).After treatment，24 h urine protein of the treatment group significantly reduced，and the difference was statistically significant (P<005).The efficiency of the treatment group was 100%，and the control group 90%，t=3157，P<005.The difference was statistically significant.Besides，patients in both groups show no adverse reactions.Conclusion：Warming kidney and dissolving turbidity and removing stasis and dredging collaterals methodcombined with conventional western medicine in the treatment of diabetic nephropathy is better than conventional western medicine treatment.
Key WordsDiabetic nephropathy； Chinese and Western medicine； Warming kidney and dissolving turbidity； Removing stasis and dredging collaterals, 百拇医药(宋诵文曾琦吴新民宋银枝)
关键词糖尿病肾病；中西医结合疗法；温肾化浊；逐瘀通络
, http://www.100md.com
Clinical Observation of Treating Diabetic Nephropathy with Warming Kidney and Dissolving Turbidity and Removing Stasis and Dredging Collaterals Method
Song Songwen1，Zeng Qi1，Wu Xinmin1，Song Yinzhi2
(1 Internal Medicine Department of Humen Chinese Medicine Hospital，Dongguan 523939，China； 2 Cardiovascular Department of Baoan Chinese Hospital，Shenzhen 523900，China)
AbstractObjective：To observe the clinical efficacy of warming kidney and dissolving turbidity and removing stasis and dredging collaterals method in the treatment of diabetic nephropathy.Methods：From February 2014 to 2016，60 patients with diabetic nephropathy in our outpatient hospital were randomly collected and divided into two groups：the treatment group(using Chinese method) and the control group(using western medicine).After 3 months of treatment，two groups were observed before and after treatment for biochemical index and symptom scores，and the therapeutic effect of two groups were compared.Results：After treatment，FBG，HbAlc，TG and other indicators have improved，before and after treatment，HbAlc，TG，24 h urine protein set，UAER of the two groups were significantly different (P<005).Before and after treatment，BuN，Cr，CysC，CH，hsCRP showed no significant difference between the two groups (P>005).After treatment，24 h urine protein of the treatment group significantly reduced，and the difference was statistically significant (P<005).The efficiency of the treatment group was 100%，and the control group 90%，t=3157，P<005.The difference was statistically significant.Besides，patients in both groups show no adverse reactions.Conclusion：Warming kidney and dissolving turbidity and removing stasis and dredging collaterals methodcombined with conventional western medicine in the treatment of diabetic nephropathy is better than conventional western medicine treatment.
Key WordsDiabetic nephropathy； Chinese and Western medicine； Warming kidney and dissolving turbidity； Removing stasis and dredging collaterals, 百拇医药(宋诵文曾琦吴新民宋银枝)
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